Know how to use it before it's needed


Read and become familiar with the Instructions for Use in the package insert before an episode occurs. If you have questions about using GlucaGen® HypoKit®, talk with your doctor or pharmacist.

If the person you are caring for becomes unconscious due to very low blood sugar, use the GlucaGen® HypoKit® kit right away. Call for emergency medical help immediately after using the kit.

Know where the person you are caring for keeps this GlucaGen® HypoKit® and how to use it. You can practice giving a shot by giving normal insulin shots. It is important that you practice. If you have never given a shot, you may not be able to give one in an emergency.

Act quickly.

Being unconscious for a period of time may be harmful. Follow these instructions to give GlucaGen® the right way.

  • Turn the unconscious person on their side to prevent choking
  • Do not mix GlucaGen® until you are ready to use it
  • Mix the GlucaGen®. The syringe does not have GlucaGen® in it. You must mix the contents of the syringe with GlucaGen® in the vial provided in the GlucaGen® HypoKit® before giving the injection (See Instructions for Use)
  • Throw away any mixed GlucaGen® that is not used

The patient may be in a coma from very high blood sugar (severe hyperglycemia), rather than very low blood sugar. If this is the case, the unconscious person will not respond to GlucaGen®.

Symptoms of severe hypoglycemia include: confusion, loss of consciousness, and seizures. Less severe cases of hypoglycemia should be treated right away by eating sugar or a sugar-sweetened product such as a regular soft drink or fruit juice.

You should only give GlucaGen® injection if:

  • the person is unconscious, or
  • the person is having a seizure, or
  • the person is confused and unable to eat sugar or a sugar-sweetened product

Hypoglycemia may happen again after receiving GlucaGen® treatment. 

GlucaGen® does not work if it is taken by mouth.


GlucaGen® is glucagon.


Important Safety Information

Who should not use GlucaGen® HypoKit®?

Do not use GlucaGen® HypoKit® if:

  • you are allergic to glucagon or lactose or any of the ingredients in GlucaGen®  HypoKit®
  • you have a tumor in the gland on top of your kidneys (adrenal gland) called a pheochromocytoma
  • you have a tumor of the pancreas called an insulinoma

What should I tell my doctor before using GlucaGen® HypoKit®?

Before using GlucaGen® HypoKit®, tell your doctor about all of your medical conditions, including if you:

  • have kidney problems
  • have pancreas problems. Tumors in your pancreas called glucagonomas
  • have not had food or water for a long time (prolonged fasting or starvation)
  • have low blood sugar that does not go away (chronic hypoglycemia)
  • have heart problems
  • are pregnant, plan to become pregnant, are breastfeeding, or plan to breastfeed. It is not known if GlucaGen® HypoKit® passes into your breast milk

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. GlucaGen® HypoKit® may affect the way other medicines work, and other medicines may affect how GlucaGen® HypoKit® works.

How should I use GlucaGen® HypoKit®?

  • Read the detailed Instructions for Use that come with GlucaGen® HypoKit®.
  • Use GlucaGen® HypoKit® exactly as your doctor tells you to.
  • Make sure that you and your family know how to use GlucaGen® HypoKit® the right way before you need it.
  • Act quickly. Having low blood sugar for a period of time may be harmful.
  • Call for emergency medical help right after you use GlucaGen® HypoKit®.
  • Eat sugar or a sugar-sweetened product such as a regular soft drink or fruit juice as soon as you are able to swallow.
  • Tell your doctor each time you use GlucaGen® HypoKit®. Your doctor may need to change the dose of your diabetes medicines.

What should I avoid while using GlucaGen® HypoKit®?

While using GlucaGen® HypoKit® do not:

  • drive or operate machinery until you have eaten sugar or a sugar-sweetened product such as a regular soft drink or fruit juice.

What are the possible side effects of GlucaGen® HypoKit®?

GlucaGen® HypoKit® may cause serious side effects, including:

  • High blood pressure. High blood pressure is common after taking GlucaGen® HypoKit® and can be severe.
  • Low blood sugar. GlucaGen® HypoKit® can cause low blood sugar in patients with tumors in their pancreas called insulinomas and glucagonomas by making too much insulin in their bodies.
  • Allergic reactions. Symptoms of a serious allergic reaction to GlucaGen® HypoKit® may include rash, difficulty breathing, or low blood pressure (hypotension).

The most common side effects of GlucaGen® HypoKit® include nausea, vomiting, temporary fast heartbeat or pounding in your chest (tachycardia).

Tell your doctor if you have any side effect that bothers you or that does not go away.

Indications and Usage

What is GlucaGen® (glucagon [rDNA origin] for injection) HypoKit®?
GlucaGen® HypoKit® is a prescription medicine used to treat very low blood sugar (severe hypoglycemia) in people with diabetes who use insulin.

Please click here for the GlucaGen® HypoKit® Prescribing Information and GlucaGen® HypoKit® Patient Information.

GlucaGen® HypoKit® is a prescription medication.

Talk to your doctor about the importance of diet and exercise in your treatment plan.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

If you need assistance with prescription drug costs, help may be available. Visit pparx.org or call 1-888-4PPA-NOW.

GlucaGen® and HypoKit® are registered trademarks of Novo Nordisk A/S.