What is glucagon?

Glucagon works by triggering the liver to release stored sugar, raising blood sugar levels. It is injected under the skin, similar to how insulin is injected.

What is GlucaGen® HypoKit®?

GlucaGen® HypoKit® is a glucagon emergency kit for the treatment of severe low blood sugar in people who have diabetes and use insulin. It is a prescription medicine that contains an injection of glucagon, a hormone that raises your blood sugar level.

Who should not use GlucaGen®?

Do not use GlucaGen® if you are allergic to either glucagon or lactose, have a tumor of the adrenal gland called a pheochromocytoma, or have a tumor of the pancreas called insulinoma.

What should I know about GlucaGen® HypoKit®?

Make sure that your family members, coworkers, or close friends know that if you become unconscious they should use this kit right away. They should call for emergency medical help immediately after using the kit.

Show your family members and others where you keep this kit and how to use it. They need to know how to use it before you need it. They can practice giving a shot by giving you your normal insulin shots. It is important that they practice. A person who has never given a shot may not be able to give one when needed.

It is important that your family member or friend act quickly. Being unconscious for a period of time may be harmful. Follow the Instructions for Use to give GlucaGen® the right way.

What are the possible side effects of GlucaGen®?

GlucaGen® may cause serious side effects including:

  • allergic reactions. Symptoms of a severe allergic reaction may include:
    • rash or itching
    • raised red patches on your skin (hives)
    • swelling of the face, lips, tongue or throat
    • problems breathing or swallowing
    • very high or very low blood pressure
    • fast or slow heartbeat

The most common side effects of GlucaGen® include:

  • nausea
  • vomiting

Tell your doctor if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of GlucaGen®. For more information, ask your doctor or pharmacist.

What are the ingredients in the GlucaGen® HypoKit®?

Active Ingredient: glucagon [rDNA origin] for injection
Inactive ingredients: lactose, sterile water for reconstitution


GlucaGen® is glucagon.


Important Safety Information

Who should not use GlucaGen® HypoKit®?

Do not use GlucaGen® HypoKit® if:

  • you are allergic to glucagon or lactose or any of the ingredients in GlucaGen®  HypoKit®
  • you have a tumor in the gland on top of your kidneys (adrenal gland) called a pheochromocytoma
  • you have a tumor of the pancreas called an insulinoma

What should I tell my doctor before using GlucaGen® HypoKit®?

Before using GlucaGen® HypoKit®, tell your doctor about all of your medical conditions, including if you:

  • have kidney problems
  • have pancreas problems. Tumors in your pancreas called glucagonomas
  • have not had food or water for a long time (prolonged fasting or starvation)
  • have low blood sugar that does not go away (chronic hypoglycemia)
  • have heart problems
  • are pregnant, plan to become pregnant, are breastfeeding, or plan to breastfeed. It is not known if GlucaGen® HypoKit® passes into your breast milk

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. GlucaGen® HypoKit® may affect the way other medicines work, and other medicines may affect how GlucaGen® HypoKit® works.

How should I use GlucaGen® HypoKit®?

  • Read the detailed Instructions for Use that come with GlucaGen® HypoKit®.
  • Use GlucaGen® HypoKit® exactly as your doctor tells you to.
  • Make sure that you and your family know how to use GlucaGen® HypoKit® the right way before you need it.
  • Act quickly. Having low blood sugar for a period of time may be harmful.
  • Call for emergency medical help right after you use GlucaGen® HypoKit®.
  • Eat sugar or a sugar-sweetened product such as a regular soft drink or fruit juice as soon as you are able to swallow.
  • Tell your doctor each time you use GlucaGen® HypoKit®. Your doctor may need to change the dose of your diabetes medicines.

What should I avoid while using GlucaGen® HypoKit®?

While using GlucaGen® HypoKit® do not:

  • drive or operate machinery until you have eaten sugar or a sugar-sweetened product such as a regular soft drink or fruit juice.

What are the possible side effects of GlucaGen® HypoKit®?

GlucaGen® HypoKit® may cause serious side effects, including:

  • High blood pressure. High blood pressure is common after taking GlucaGen® HypoKit® and can be severe.
  • Low blood sugar. GlucaGen® HypoKit® can cause low blood sugar in patients with tumors in their pancreas called insulinomas and glucagonomas by making too much insulin in their bodies.
  • Allergic reactions. Symptoms of a serious allergic reaction to GlucaGen® HypoKit® may include rash, difficulty breathing, or low blood pressure (hypotension).

The most common side effects of GlucaGen® HypoKit® include nausea, vomiting, temporary fast heartbeat or pounding in your chest (tachycardia).

Tell your doctor if you have any side effect that bothers you or that does not go away.

Indications and Usage

What is GlucaGen® (glucagon [rDNA origin] for injection) HypoKit®?
GlucaGen® HypoKit® is a prescription medicine used to treat very low blood sugar (severe hypoglycemia) in people with diabetes who use insulin.

Please click here for the GlucaGen® HypoKit® Prescribing Information and GlucaGen® HypoKit® Patient Information.

GlucaGen® HypoKit® is a prescription medication.

Talk to your doctor about the importance of diet and exercise in your treatment plan.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

If you need assistance with prescription drug costs, help may be available. Visit pparx.org or call 1-888-4PPA-NOW.

GlucaGen® and HypoKit® are registered trademarks of Novo Nordisk A/S.